Tamoxifen citrate is an anti estrogen drug which is non-steroidal in which it typically inhibits the estrogen receptors of a specific tumor or organ in the body. The fighting mechanism of Tamoxifen citrate is that it prevents the hypertrophy of the body cells in which it is dependent by the estrogen’s regulation. Tamoxifen citrate effects will occur after several weeks from the first dose. In most women, this drug can stimulate or motivate the production of hormones called gonadotropic in the hypophysis. In men, Tamoxifen citrate increases the production of hormone that stimulates the follicle and increase also the concentration of testosterone, luteinizing hormone, and the blood-serum’s estrogen especially for thoe men who have oligospermia.
But the most common application of the drug Nolvadex or Tamoxifen citrate is on breast cancer. It is used for the treatment in both women and men suffering from breast cancer, especially after breast cancer operation called castration for the purpose of preventing the cancer cells from further development and spreading in the entire body. Tamoxifen citrate is also a treatment for some conditions such as melanomas, cancer of the kidney, cancer of the ovary, and soft tissues’ sarcomas that contains estrogen receptors.
Tamoxifen citrate is a drug that should be taken with caution. The amount dosage per patient should only be determined by a doctor. A patient must only take the recommended dosage that depends upon his or her condition. Usually, two (2) years is the typical period of duration of Tamoxifen citrate’s medication according to healthcare providers so that the re-occurrence of cancer will not happen anymore, but just like any other drugs, taking up medication like this will not give assurance that the cancer will never come back nor the patient will recover totally, remember that cancer is a traitor disease and currently there is no drug ever invented that totally eliminates cancer. Tamoxifen citrate will just be some kind of a supplement drug and a preventive drug that controls the worsening of a certain condition.
Tamoxifen citrate is usually taken in a single dose per day with a full stomach, it can also be divided into two that can be taken twice daily and the drug should be absorbed within the body naturally, meaning it should never be chewed to attain its normal concentration effect on our body. But just like any other drugs, the medication with this drug could open or increase the possibility for endometrial cancer. Also, patients should always have the guidance of a doctor during medication so that a patient can be monitored for any abnormal body effects like menstrual cycle change, vaginal bleeding, pelvic pressure and pain, and excessive vaginal discharge.
Also this drug is contradicted for Tamoxifen citrate hypersensitive patients. Women having anticoagulant therapy that is of coumarine-type, breastfeeding or pregnant women, and deep vein thrombosis must also avoid this medication. Also, patients suffering from hyperlipidemia, eye diseases, hypercalcemia, thrombocytopenia, thromboembolism, and severe thrombophlebitis should take Tamoxifen citrate with caution.